Saikosaponin C
Saikosaponin C
CAS: 20736-08-7
Molecular Formula: C48H78O17
Saikosaponin C - Names and Identifiers
| Name | Saikosaponin C |
| Synonyms | Saikosaponin C SAIKOSAPONIN C Saikosaponian C chikusakoside II SAIKOSAPONIN C(P) Saikosaponin C 20736-08-7 [13,28-Epoxy-16β-hydroxyolean-11-en-3β-yl]4-O-(6-deoxy-α-L-mannopyranosyl)-6-O-(β-D-glucopyranosyl)-β-D-glucopyranoside b-D-Glucopyranoside, (3b,16b)-13,28-epoxy-16-hydroxyolean-11-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(14)-O-[b-D-glucopyranosyl-(16)]- (3beta,4alpha,16beta)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-4)-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranoside |
| CAS | 20736-08-7 |
| InChI | InChI=1/C48H78O17/c1-22-30(51)32(53)36(57)40(61-22)65-38-24(20-59-39-35(56)33(54)31(52)23(19-49)62-39)63-41(37(58)34(38)55)64-29-11-12-44(6)25(43(29,4)5)9-13-45(7)26(44)10-14-48-27-17-42(2,3)15-16-47(27,21-60-48)28(50)18-46(45,48)8/h10,14,22-41,49-58H,9,11-13,15-21H2,1-8H3/t22-,23+,24+,25-,26+,27+,28-,29-,30-,31+,32+,33-,34+,35+,36+,37+,38+,39+,40-,41-,44-,45+,46-,47+,48-/m0/s1 |
Saikosaponin C - Physico-chemical Properties
| Molecular Formula | C48H78O17 |
| Molar Mass | 927.12 |
| Density | 1.40±0.1 g/cm3(Predicted) |
| Melting Point | 310-314 °C(Solv: methanol (67-56-1)) |
| Specific Rotation(α) | (EtOH)+4.3 |
| Solubility | Easily soluble in water, dilute alcohol, especially hot water and hot alcohol, highly soluble in butanol and pentanol, insoluble or insoluble in benzene, ether, chloroform and other solvents. |
| Appearance | White powder |
| Color | White to Off-White |
| pKa | 12.76±0.70(Predicted) |
| Storage Condition | Refrigerator, under inert atmosphere |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.623 |
| MDL | MFCD00075673 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the aerial part of bupleurum. |
Saikosaponin C - Reference
| Reference Show more | 1. Min Yuhang, Wang Jinghui, Fan Miaoxuan, et al. Study on Composition Changes and Quality Control of Saponins in Bupleurum Decoction Pieces [J]. Journal of Drug Analysis, 2014, 034(005):836-843. 2. Cai Hua, Ye Fang, Yang Guangyi, Du Shiming, Wang Gang, Du Ting, Sun Rongjin. Dynamic Changes of Effective Components in Bupleurum chinense at Different Harvest Periods [J]. Research and Practice of Modern Traditional Chinese Medicine, 2013,27(06):27-29 21. 3. Cai Hua, Ye Fang, Huang Liangyong, et al. Study on Characteristic Fingerprint of Bupleurum by Ultra Performance Liquid Spectrometry [J]. Chinese Journal of Hospital Pharmacy, 2014, 34(005):359-364. 4. Cai Hua, Ye Fang, Yang Guangyi, et al. Study on Fingerprint of Bupleurum UPLC-MS of Bamboo Leaf and Bupleurum in Northwest Hubei [J]. Chinese Pharmacist, 2014(05):797-800. 5. Xia Yanming, Dong Ying, Di Liuqing, et al. Simultaneous Determination of Four Saikosaponins in Xiaozheng Pellets by One Test and Multiple Evaluation Method [J]. Chinese patent medicine, 2017, 39(008):1620-1625. 6. Guo Shuangshuang Zheng Fangfang Ke Cong Xue et al. Analysis of Enzymatic Properties of α-L-rhamnosidase from Pediococcus Lactate AS1.2696 [J]. Food Science 2019 040(004):160-169. 7. Dong Xiaoke, Liu Jinmin, Li Zhonghao, Yuan Siyuan, Wang Kaiyue, Li Lili, Zheng Xiangchun. Study on the main blood components of Chaibei Zhixian Decoction in rats and its pharmacokinetics [J]. Global Chinese Medicine, 2021,14(03):377-383. 8. [IF = 3.882] Kunpeng Yin et al."Lanthanide Metal-Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine." Langmuir. 2021;37(17):5321-5328 |
Saikosaponin C - Reference Information
| Biological activity | Saikosaponin C is the active ingredient in Bupleurum, and its main target in Alzheimer's disease acts on amyloid beta and tau proteins. Saikosaponin C inhibited the release of Aβ1-40 and Aβ1-42, inhibited the phosphorylation of abnormal tau protein, but had no effect on the activity and expression of BACE1. |
| use | used for content determination/identification/pharmacological experiments, etc. Pharmacological effect: It has obvious hypnotic effect. Saikosaponins such as Saikosaponin C are used to help analyze and solve the active mechanism of Chinese medicinal materials, such as Xiaochaihu Decoction. |
Last Update：2024-04-09 21:04:16
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Product Name: Saikosaponin C Visit Supplier Webpage Request for quotationCAS: 20736-08-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Saikosaponin C Visit Supplier Webpage Request for quotationCAS: 20736-08-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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